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Lung cancer susceptibility
Lung cancer susceptibility tests suggest the probability or susceptibility an individual may have of getting lung cancer. Lung cancer is a disease characterized by uncontrolled cell growth in the lung tissue. If left untreated, this growth can spread beyond the lungs in a process called metastasis, into nearby tissues or other parts of the body.
== Lung cancer and genetics ==
Lung cancer is one of the most lethal and common forms of cancer worldwide. Pollution, smoking (active and passive), radiation (in the form of x-rays or gamma rays) and asbestos are risk factors for lung cancer. Symptoms may include persistent cough, chest pain, coughing up blood, fatigue, and swelling of the neck and face. There are different types of lung cancers, which can metastasize. Treatments include chemotherapy, surgery, and radiation. The treatment aimed at killing the cancer can also eliminate functioning lung cells (leukocytes).
Specific genetic factors can add to the risk of developing lung cancer. There are regions on chromosomes which are highly susceptible to mutation and, if present, increase the risk of developing lung cancer. These loci are the specific locations of a gene or a DNA sequence on a chromosome. Several loci are associated with an increased risk of developing lung cancer.〔
Approximately 26 different genes can mutate into one type of lung cancer, known as carcinoma. An example is the MAP pathway, which is inhibited by ME (a lung cancer treatment). The risk of developing lung cancer is higher for those with a family history of the disease. A second way the risk could go up is if the individual lives with a smoker.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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